隗健凯

发布者:刘明港发布时间:2020-06-26浏览次数:112


隗健凯 博士 硕士生导师

E-mail: weijiankai@ouc.edu.cn


教育及工作背景:

20069-20107月,厦门大学,海洋科学专业,学士

20109-20157月,中国科学院海洋研究所,海洋生物学专业,博士

201510-201810月,中国海洋大学,海洋生命学院,博士后

20159-至今,中国海洋大学,海洋生命学院,讲师


主要研究方向:

研究集中在海洋动物组织器官发育及环境适应的组学基础。主要以海鞘等模式动物为材料,利用基因组学、转录组学、代谢组学、基因编辑、细胞成像等技术,探索海洋动物幼体形态发生和适应性进化的分子机制。研究结果发表在Biology Open, Marine Genomics, BMC Genomics等国际主流期刊。


Dr. Jiankai WEI:

2006.09 - 2010.07: B.S. in Oceanography, Xiamen University, China;

2010.09 - 2015.07: Ph.D. in Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, China;

2015.10 - 2018.10: Post-doc researcher with Prof. Bo Dong, College of Marine Life Sciences, Ocean University of China, China;

2015.09 -: Lecturer, College of Marine Life Sciences, Ocean University of China, China.


Research focus

The research interest is genomic basis of development and adaptions of marine animals. We mainly use ascidians as models to understand the molecular mechanisms of morphogenesis and adaptive evolution. Currently, we are applying integrated high-throughput genomic sequencing in ascidians and their microbiomes to understand their environmental adaptions, and single-cell transcriptomic sequencing to dissect the key regulators during organogenesis.


Selected publications

Jiankai Wei, Bo Dong*, Identification and expression analysis of long noncoding RNAs in embryogenesis and larval metamorphosis of Ciona savignyi. Marine Genomics, 2018, 40:64-72.

Jiankai Wei, Guilin Wang, Xiang Li, Ping Ren, Haiyan Yu, Bo Dong*, Architectural delineation and molecular identification of extracellular matrix in ascidian embryos and larvae. Biology Open, 2017, 6(9):1383-1390. (cover )

Jiankai Wei, Richard Samuel Elliot Glaves, Melony J. Sellars, Jianhai Xiang, Philip L. Hertzler*, Expression of the prospective mesoderm genes twist, snail, and mef2 in penaeid shrimp, Development Genes and Evolution, 2016, 226(4):317-324

Jiankai Wei, Xiaojun Zhang, Yang Yu, Hao Huang, Fuhua Li, Jianhai Xiang*, Comparative transcriptomic characterization of the early development in pacific white shrimp Litopenaeus vannamei, Plos One, 2014, 9(9):e106201

Jiankai Wei, Xiaojun Zhang*, Yang Yu, Fuhua Li, Jianhai Xiang, RNA-Seq reveals the dynamic and diverse features of digestive enzymes during early development of Pacific white shrimp Litopenaeus vannamei, Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 2014, 11:37-44

Ping Ren#, Jiankai Wei#, Haiyan Yu, Bo Dong*, Identification and functional characterization of solute carrier family 6 genes in Ciona savignyi. Gene 2019, 705:142-148.

Philip L. Hertzler*, Jiankai Wei, Andrew P. Droste, Jianbo Yuan, Jianhai Xiang, Penaeid shrimp brachyury: sequence analysis and expression during gastrulation, Development Genes and Evolution, 2018, 228:219-225

Yi Gao, Jiankai Wei, Jianbo Yuan, Xiaojun Zhang*, Fuhua Li, Jianhai Xiang*, Transcriptome analysis on the exoskeleton formation in early developmental stages and reconstruction scenario in growth-moulting in Litopenaeus vannamei, Scientific Reports, 2017, 7:1098

Yang Yu, Jiankai Wei, Xiaojun Zhang, Jingwen Liu, Chengzhang Liu, Fuhua Li*, Jianhai Xiang. SNP discovery in the transcriptome of white Pacific shrimp Litopenaeus vannamei by next generation sequencing. Plos One 2014, 9(1):e87218

Yi Gao, Xiaojun Zhang, Jiankai Wei, Xiaoqing Sun, Jianbo Yuan, Fuhua Li, Jianhai Xiang*, Whole transcriptome analysis provides insights into molecular mechanisms for molting in Litopenaeus vannamei, PLos One, 2015, 10(12):e0144350

Xiaoming Zhang, Xiaozhuo Liu, Chengzhang Liu, Jiankai Wei, Haiyan Yu, Bo Dong*, Identification and characterization of microRNAs involved in ascidian larval metamorphosis, BMC Genomics, 2018, 19:

Jianbo Yuan, Yi Gao, Xiaojun Zhang*, Jiankai Wei, Chengzhang Liu, Fuhua Li, Jianhai Xiang*, Genome sequences of marine shrimp Exopalaemon carinicauda Holthuis provide insights into genome size evolution of Caridea. Marine Drugs, 2017, 15(7)

Jianbo Yuan, Xiaojun Zhang*, Chengzhang Liu, Jiankai Wei, Fuhua Li, Jianhai Xiang*, Horizontally transferred genes in the genome of Pacific white shrimp, Litopenaeus vannamei, BMC Evolutionary Biology, 2013, 13:165

Punit Bhattachan, James Rae, Haiyan Yu, WooRam Jung, Jiankai Wei, Robert G*. Parton, Bo Dong*, Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. FASEB Journal 2020, 34(1):1345-1361.

Jianbo Yuan, Xiaojun Zhang*, Chengzhang Liu, Yang Yu, Jiankai Wei, Fuhua Li, Jianhai Xiang*, Genomic resources and comparative analyses of two economical penaeid shrimp species, Marsupenaeus japonicus and Penaeus monodon, Marine Genomics, 2018, 39:22-25

Qingli Zhang, Jie Huang, Fuhua Li, Shuang Liu, Qinghui Liu, Jiankai Wei, Gaofeng Liang, Jianhai Xiang*, Molecular characterization, immune response against white spot syndrome virus infection of peroxiredoxin 4 in Fenneropenaeus chinensis and its antioxidant activity, Fish & Shellfish Immunology, 2014, 37(1):38-45