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         中国海洋大学达尔文馆
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Darwin Building, Ocean University

of China
5 Yushan Road
Qingado 266003, China
Tel: +86 532 8203 1982
E-mail:zhangc@ouc.edu.cn

  • 研究所简介 Introduction

海洋生物多样性与进化研究所

简 介

  

空格

海洋生物多样性与进化研究所于2010年2月成立,作为校内跨院组合机构和海洋生物学国家重点学科、生物学一级学科博士点的构成之一,所内各团队主要聚焦于海洋重要模式生物、重要功能类群的多样性、发育与进化等基础理论领域,整合了中国海洋大学有关学术团队和人力资源,搭建了一个集多样性、进化与模式动物发育为一体的跨院系研究大平台,并在纤毛虫学、模式动物发育与进化、表观遗传学、海洋生物进化与多样性等领域取得了国内外公认的成就。


研究所目前人员总数为 45人,包括教授24人,副教授12人、讲师5人、实验系列3人、行政管理人员1人。其中中国科学院院士、教育部“长江学者”、“国家杰出青年基金”获得者、山东省“泰山学者”特聘教授、“山东省杰出青年基金”获得者、国家“优青”、“青年千人”获得者、教育部“新世纪人才计划”入选者14人。


主要研究方向与领域

原核与真核微生物多样性与进化生物学

围绕纤毛虫原生动物的多样性、细胞学、系统发育、表观遗传学、基因进化等基础生物学问题,主要研究包括:(1)聚焦在我国温带、亚热带-热带沿海自由生活类群,研究其区系、多样性、群落结构演变、生态学功能与地位、时空与地理分布;(2)探讨旋唇纲等高等分化类群无性生殖期间细胞器结构分化及模式的形成与演化规律;(3)利用分子与个体发育信息,探讨纤毛门内各纲--科级等高阶阶元间的亲缘关系及大尺度的系统发育与演化;(4)以四膜虫为材料,围绕以组蛋白翻译后修饰为主的表观遗传学,阐明甲基化酶在DNA复制延伸中的作用,揭示四膜虫大小核分化的调控通路;(5)开展纤毛虫各代表类群的DNA建库、纤毛虫条形码基因的筛选、标记性基因测序、大小核的基因进化及重要类群的组学信息构建与分析。

模式动物的发育与进化

以模式动物为材料,研究动物发育、再生过程中的基因表达、功能、调控网络和信号通路以及免疫系统、化学感受器等构成、作用和演化规律等。主要方向包括:(1)以文昌鱼、斑马鱼等为模式动物,从组织、细胞、分子等层次研究神经内分泌、免疫和味觉系统的起源与演化,勾画脊椎动物起源与进化图景;从基因和蛋白水平上探讨机体与器官的发育及衰老的分子机理;(2)以斑马鱼为模式生物,围绕眼睛、肾脏等重要器官,解析纤毛的发生机理及其缺陷所引起的器官发育异常的分子机制;(3)以海鞘和果蝇为模式,开展管腔器官形态发生、信号通路调控等研究,旨在阐明管腔器官发育的细胞学过程及其分子调控机制;通过对胚胎发育过程中的器官发生和基因表达的研究,揭示HhTGF等重要发育信号通路的转导机制和调控机理;(4)研究对虾细胞的体外培养技术、基因转移技术和体外培养细胞的生长停滞问题以及文昌鱼和蝾螈的附肢再生、组织器官再生的细胞和分子机制以及进化规律;(5)开展海洋藻类基因变异的创制、甄别和开发利用以及顺应和适应环境变化的生理机制和遗传基础;(6)开展鱼类比较和进化免疫学研究,解析关键免疫分子(家族)的结构和功能多样性发生与进化机制。

重要进化节点生物的多样性与系统演化

研究海洋原核及真核生物中的物种、基因多样性,结合形态和分子特征探讨其起源与进化。主要方向包括:(1)聚焦中国沿海纽形动物、头足动物、棘皮动物等无脊椎动物类群,开展形态与分子相结合的分类研究,构建物种的DNA条形码库,解析系谱间的系统发育关系,通过比较生物学、系统生物地理学和组学分析等探讨种下进化与物种形成、解析动物结构与功能关系及适应进化;(2)研究中国近海、极地、深渊等海域浮游病毒多样性、群落结构、功能及其与宿主、环境因子之间的相互作用,构建不同海洋环境的浮游病毒宏基因组及宏转录组数据库,开展噬菌体基因组分析;研究微型、微微型浮游生物多样性、群落结构组成及功能;(3)聚焦深海海沟、热液喷口、边缘海等典型海区的细菌和古菌等微生物,利用系统微生物组等手段,开展海洋微生物的多样性、生物地理学、环境适应机理和生物地球化学作用研究;(4)珊瑚、海绵及其共生微生物的多样性与系统发育、次级代谢产物结构与功能多样性及其化学生态作用机制;(5)利用组学技术与方法,结合群体遗传学理论,以海洋细菌、酵母和原生生物为研究对象,研究自发变异产生的机制及变异率的演化规律



Institute of Evolution & Marine Biodiversity, OUC

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Inaugurated in February 2010, the Institute of Evolution & Marine Biodiversity (IEMB) is an inter-department institution mainly focusing on studies of biodiversity, developmental biology and evolution of marine organisms. IEMB is one of the doctorate authorization spot of National Key Discipline of Marine Biology with doctoral program covering all fields of biology. IEMB has received international acclaims on several cutting-edge researches including ontogeny, phylogeny and biodiversity of marine ciliated protozoa and developmental biology and immunology studies of protochordates.

Currently, IEMB has 36 faculty and staff members, including 21 full professors.  Members of  IEMB have won many academichonours, titles andawards, including Academician of Chinese Academy of Sciences, Cheung Kong ScholarTaishan Scholar” and the winner of Outstanding Young Scientists of China.

  

Main current research fields:

●Evolutionary biology and biodiversity of prokaryotic and eukaryotic microbes

Centered on studies of biodiversity, cytology, phylogeny,epigenetics, and gene evolution of ciliated protozoa, the main research interests include: (1) fauna, species and gene diversity, community structure and ecological functions in ecosystem, temporal/geographic distribution of free-living ciliates in temperate and subtropical/tropical coastal areas; (2) developmental modes and pattern-formation, ontogenesis of ciliates during cell division; (3) relationships and systematic positions of taxa at class-order-family level within the phylum Ciliophora; (4) epigenetic regulatory mechanisms in gene replication and transcription, using Tetrahymena as model organism; (5) construction of the DNA library of marine forms, sequencing marker genes, barcoding gene selection and barcoding database construction, gene evolution between macro- and micronucleus, as well as omics analyses from representative taxa.

Evolution and development of model animals

Our mission emphasizes a creative, inter-discipline approach to the fundamental research into the mechanisms of evolution and development, especially organogenesis and regenerationutilizing zebrafish, Drosophila, amphioxus, marine tunicate and algae as model animals.Our currentresearch interests include: (1) origin and evolution of neuroendocrine, immune and gustatory systems; (2) cellular processes, signal transduction and regulatory mechanisms of cilia biogenesis and related diseases, biological tube formation, agingandliverdevelopment; (3) growth-arrested mechanisms and immortalization of the cultured cells, and cellular and molecular mechanisms as well as evolutionary history of tissue/organ regeneration; (4) genetic bases and physiological mechanisms underlying environmental adaptation; (5) evolution of structure and function of key immune molecules.

Diversity and systematics of marine organisms

Studyingmarine organisms’morphology, taxonomy,biodiversity, genomics, phylogeny, and population genetics.The main research interests include:(1) biodiversity, community structure and function of virioplanktons as well as their interaction with hosts and environmental factors in China's offshore, polar and deep-sea waters, construction of the metagenomic and transcriptomic databases of virioplanktons in different marine contexts; isolation, purification and genome analysis of strains of cyanophages and their hosts; discovery of novel strains and genes of viruses; picoeukaryotic biodiversity and community structure; (2) diversity, biogeography, biogeochemistry (including carbon, nitrogen and sulphur cycles) and the environmental adaptation of marine microorganisms (bacteria and archaea) in typical sea habitats such as deep-sea trench, hydrothermal vents and marginal seas; (3) spontaneous mutagenesis and mutation rate evolution of marine microbial organisms, such as bacteria, yeasts and protists; (4) biodiversity and phylogeny of corals and poriferans, their microbial symbionts; structural and functional diversity and chemical ecology of their secondary metabolites; (5) morphology, taxonomy, DNA barcoding, phylogeography, speciation and evolution of selected marine invertebrates, such as nemerteans, cephalopods and echinoderms.

  

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