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海洋生物多样性与进化研究所
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  • 关于IEMBAbout IEMB
    • 研究所简介Introduction
    • 组织框架Framework
    • 教授委员会Professor Committee
    • 研究所成员Staff
  • 研究团队Research Groups
    • 原生动物学团队Protozoology Team
      • 原生动物学研究室Laboratory of Protozoology
      • 染色体生物学实验室Laboratory of Chromosome Biology
      • 系统分类学实验室Laboratory of Systematic Taxonomy
    • 发育生物学团队Developmental Biology Team
      • 进化与发育实验室Laboratory for Evolution & Developmental Biology
      • 纤毛与器官发育实验室Laboratory of Cilia Biology & Organogenesis
      • 发育与再生生物学实验室Laboratory of Developmental & Regenerative Biology
      • 细胞与组织动力学实验室 Laboratory of Cell & Tissue Dynamics
    • 演化生物学团队 Evolutionary Biology Team
      • 形态发生与进化实验室Laboratory for Morphogenesis & Evolution
      • 水生寄生虫学实验室Laboratory of Aquatic Parasitology
      • 进化基因组学实验室 Laboratory of Evolutionary Genomics
      • 海洋化能合成生态系统实验室Chemosynthetic Ecosystems Laboratory
      • 头足类分类与系统演化实验室 Laboratory of Cephalopod Taxonomy & Phylogeny
      • 海洋生物整合组学实验室 Laboratory of Integrative Omics of Marine Organisms
    • 生态与环境生物学团队Ecology & Environmental Biology Team
      • 微生物海洋学实验室 Laboratory of Microbial Oceanography
      • 海洋病毒与微型生物多样性实验室 Laboratory of Viral & Microbial Diversity
      • 环境微生物生态实验室Laboratory of Environmental Microbial Ecology
      • 底栖生物实验室Laboratory of Benthos
    • 海洋生物资源学团队Marine Bioresources Team
      • 海洋药用资源生物学实验室 Laboratory of Marine Medical Resources Biology
      • 可持续生物材料实验室Laboratory of Sustainable Biomaterials
      • 海洋生物被膜实验室Laboratory of Marine Biofilms
    • 细胞生物学团队Cell Biology Team
      • 藻类遗传学实验室Laboratory of Algal Genetics
      • 藻类病理学实验室Laboratory of Algal Pathology
      • 海洋动物细胞培养技术实验室Laboratory of Cell Culture Technology of Marine Animals
      • 再生生物学实验室Laboratory of Regenerative Biology
      • 海洋微生物互作实验室Laboratory of Marine Microbial Interaction
  • 科学研究Research
    • 科研进展New Achievements
    • 发表论文Publications
  • 研究生招生Admissions
    • 招生信息For Prospective Students
    • 导师信息Advisors
      • 博士生导师Ph.D. advisors
      • 硕士生导师Master's advisors
  • 运行管理Management
    • 设备预约Equipment Reservation
    • 实验室安全Laboratory Safety
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研究团队
Research Groups

  • 原生动物学团队
    Protozoology Team
    • 原生动物学研究室
      Laboratory of Protozoology
    • 染色体生物学实验室
      Laboratory of Chromosome Biology
    • 系统分类学实验室
      Laboratory of Systematic Taxonomy
  • 发育生物学团队
    Developmental Biology Team
  • 演化生物学团队
    Evolutionary Biology Team
  • 生态与环境生物学团队
    Ecology & Environmental Biology Team
  • 海洋生物资源学团队
    Marine Bioresources Team
  • 细胞生物学团队
    Cell Biology Team
  • 近期论文及成果(研究室主页链接请点击:http://scxy.ouc.edu.cn/lplb/
    Laboratory of Protozoology

  • 当前位置:首页  研究团队  原生动物学团队  原生动物学研究室  近期论文及成果

2025 Wang Y.Y., Nan B., Ye F., Zhang Z., Yang W.T., Pan B., Wei F., Duan L.L., Li H.C., Niu J.H., Ju A.L., Liu Y.Q., Wang D.T., Zhang W.X., Liu Y.F., Gao S. Dual modes of DNA N6-methyladenine maintenance by distinct methyltransferase complexes. PNAS, 122(3): e2413037121.

2025 Ye F., Chen X., Li Y.Q., Ju A.L., Sheng Y.L., Duan L.L., Zhang J.C., Zhang Z., Al-Rasheid K.A.S., Stover N.A., Gao S. Comprehensive genome annotation of the model ciliate Tetrahymena thermophila by in-depth epigenetic and transcriptomic profiling. Nucleic Acids Research, gkae1177.

2025 Duan L.L., Li H.C., Ju A.L., Zhang Z., Niu J.H., Zhang Y.M., Diao J.H., Liu Y.Q., Ma H.G., Song N., Kataoka K., Gao S., Wang Y.Y. Methyl-dependent auto-regulation of the DNA N6-adenine methyltransferase AMT1 in the unicellular eukaryote Tetrahymena thermophila. Nucleic Acids Research, gkaf022.

2025 Jiang Y.H., Chen X., Wang C.D., Lyu L.P., Al-Farraj S.A., Stover N.A., Gao F. Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches. Science China Life Sciences, 68, 232–248.

2025 Zheng W., Li C., Zhou Z.R., Chen X., Lynch M., Yan Y. Unveiling an ancient whole-genome duplication event in Stentor, the model unicellular eukaryotes. Science China Life Sciences, DOI: 10.1007/s11427-024-2651-2.

2024 Wang C.D., Lyu L.P., Solberg T., Zhang H.Y., Wen Z., Gao F. GTSF1 is required for transposon silencing in the unicellular eukaryote Paramecium tetraurelia. Nucleic Acids Research,52: 13206–13223.

2024 Liu Y.Q., Niu J.H., Ye F., Solberg T., Lu B.R., Wang C.D., Nowacki M., Gao S. Dynamic DNA N6-adenine methylation (6mA) governs the encystment process, showcased in the unicellular eukaryote Pseudocohnilembus persalinus. Genome Research, 34(2): 256−271.

2024 Sheng Y.L., Wang Y.Y., Yang W.T., Wang X.Q., Lu J.W., Pan B., Nan B., Liu Y.Q., Ye F., Li C., Song J.K., Dou Y.L., Gao S., Liu Y.F. Semiconservative transmission of DNA N6-adenine methylation in a unicellular eukaryote. Genome Research, 34(5): 740−756.

2024 Gao Y.Y., Solberg T., Wang R., Yu Y.E., Al-Rasheid K., Gao F. Application of RNA interference and protein localization to investigate housekeeping and developmentally regulated genes in the emerging model protozoan Paramecium caudatum. Communications Biology, 7, 204.

2024 Li T., Zhang T., Liu M., Zhang Z., Zhang J., Niu J., Chen X., AlFarraj S.A., Song W.B.  Findings on three endocommensal scuticociliates (Protista, Ciliophora) from freshwater mollusks, including their morphology and molecular phylogeny with descriptions of two new species. Marine Life Science & Technology, 6: 212-235.

2023 Pan B., Ye F., Li T., Wei F., Warren A., Wang Y.Y., Gao S. Potential role of N6-adenine DNA methylation in alternative splicing and endosymbiosis in Paramecium bursaria. iScience, 26(5): 106676.

2023 Gao Y.Y., Solberg T., Wang, C.D., Gao F. Small RNA-mediated genome rearrangement pathways in ciliates. Trends in Genetics, 39(2): 94−97.

2023 Lu B.R., Hu X.Z., Warren A., Song W.B., Yan Y. From oral structure to molecular evidence: new insights into the evolutionary phylogeny of the ciliate order Sessilida (Protista, Ciliophora), with the establishment of two new families and new contributions to the poorly studied family Vaginicolidae. Science China Life Sciences, 66: 1535–1553.

2022 Wang C.D., Solberg T., Maurer-Alcalá X.X., Swart C.E., Gao F., Nowacki M. A small RNA guided PRC2 complex eliminates DNA as an extreme form of transposon silencing. Cell Reports, 40: 111263.

2022 Qiao Y., Cheng T., Zhang J., Alfarraj S.A., Tian M., Liu Y. & Gao S. Identification and utilization of a mutated 60S ribosomal subunit coding gene as an effective and cost-efficient selection marker for Tetrahymena genetic manipulation. International Journal of Biological Macromolecules, 204: 1−8.

2022 Ma M.Z., Xu Y., Lu B.R., Li Y.Q., Song W.B., Petroni G., Al-Farrah SA., & Yan Y. Molecular Phylogeny and taxonomy of four Remanella species (Protozoa, Ciliophora): a flagship genus of karyorelictean ciliates, with descriptions of three new species. Zoological Research, 43: 827−842.

2022 Ma M.Z., Li Y.Q., Maurer-Alcala X., Wang Y.R. & Yan Y. Deciphering phylogenetic relationships in class Karyorelictea (Protista, Ciliophora) based on updated multi-gene information with establishment of a new order Wilbertomorphida n. ord. Molecular Phylogenetics and Evolution, 169: 107406.

2022 Zhang G.A.T., Zhao Y., Chi Y., Warren A., Pan H.B. & Song, W.B. Updating the phylogeny and taxonomy of pleurostomatid ciliates (Protista: Ciliophora) with establishment of a new family, a new genus and two new species. Zoological Journal of the Linnean Society, 196: 105–123.

2021 Xu J., Zhao X.L., Mao F.B., Basrur V., Ueberheide B., Chait B.T., Allis C.D., Taverna S.D., Gao S., Wang W. & Liu Y. A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies. Nucleic Acids Research, 49, 5407–5425.

2021 Zheng W.B., Wang C.D., Lynch M. & Gao S. The compact macronuclear genome of the ciliate Halteria grandinella: a transcriptome-like genome with 23,000 nanochromosomes. mBio, 12: e01964-20.

2021 Chi Y., Chen X., Li Y., Wang C., Zhang T., Ayoub A., Warren A., Song W. & Wang Y.Y. New contributions to the phylogeny of the ciliate class Heterotrichea (Protista, Ciliophora): analyses at family-genus level and new evolutionary hypotheses. Science China Life Sciences, 64: 606–620.

2021 Liu Y., Nan B., Niu J., Kapler G. & Gao S. An optimized and versatile counter-flow centrifugal elutriation workflow to obtain synchronized eukaryotic cells. Frontiers in Cell and Developmental Biology, 9: 664418.

2021 Wang, C.D., Gao, Y.Y., Lu, B.R., Chi, Y., Zhang, T.T., El-Serehy, H. A., Al-Farraj, S. A., Li, L.F., Song, W.B. & Gao, F. Large-scale phylogenomic analysis provides new insights into the phylogeny of the class Oligohymenophorea (Protista, Ciliophora) with establishment of a new subclass Urocentria nov. subcl. Molecular Phylogenetics and Evolution, 159: 107112.

2021 Zhang T.T., Li C., Zhang X., Wang C.D., Roger A.J. & Gao F. Characterization and comparative analysis of mitochondrial genomes in single-celled eukaryotes shed light on the diversity and evolution of the linear molecular architecture. International Journal of Molecular Science, 22: 2546.

2021 Ma M.Z., Xu Y., Yan Y., Li Y.Q., Warren A. & Song W.B. Taxonomy and molecular information of four karyorelictids in genera Apotrachelocerca and Tracheloraphis (Protozoa, Ciliophora), with notes on their systematic positions and description of two new species. Zoological Journal of the Linnean Society, 192: 690–709.

2021 Sheng Y., Pan B., Wei F., Wang Y.Y. & Gao S. Case study of the response of N6-methyladenine DNA modification to environmental stressors in the unicellular eukaryote Tetrahymena thermophila. mSphere, 6: e01208-20.

2020 Sheng Y., Duan L., Cheng T., Qiao Y., Stover N.A., Gao S. The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses. Science China Life Sciences, 63: 1534–1542. 

2020 Zheng W., Chen J., Doak T.C., Song W.B., Yan Y. ADFinder: accurate detection of programmed DNA elimination using NGS high-throughput sequencing data. Bioinformatics, 36: 3632–3636.

2020 Chi Y., Duan L.L., Luo X.T., Cheng T., Warren A., Huang J. & Chen X.R. A new contribution to the taxonomy and molecular phylogeny of three freshwater, well-known species of the ciliate genus Spirostomum (Protozoa: Ciliophora: Heterotrichea). Zoological Journal of the Linnean Society, 189:158–177.


地址:青岛市鱼山路5号 中国海洋大学达尔文馆 邮编: 266003Tel/Fax: +86 532 8203 1982

Ocean University of China, Yushan Campus, No. 5 Yushan Road,Qingdao 266003,China,E-mail: zhangc@ouc.edu.cn

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