梁宇君 Dr. Yujun LIANG

发布时间:2016-06-22浏览次数:1010


  

所属研究团队

梁宇君 博士,讲师

E-mail: liangyujun@ouc.edu.cn

Tel:13370819230

研究方向:

再生是个神奇的生物学现象,是生物进化过程中保留下来祖先的特征,围绕组织器官再生的细胞和分子机制以及再生的进化机制这些重要科学问题,(1)以头索动物文昌鱼为材料,研究生物再生的分子和进化机制;(2)以两栖类蝾螈为材料研究器官、组织再生过程中分子和细胞学机制;(3)研究鱼类鳍的再生过程中的基因调控和细胞外基质重塑。

  

主要成果:

承担山东省自然科学基金面上项目和教育部留学归国启动基金项目,在国内外主流刊物发表论文20余篇,参加编写专著2部。曾获教育部自然科学奖一等奖一项(第二,2010年)。

  

发表研究论文:
1. Pathirana A, Diao M, Huang S, Zuo L, Liang Y*. Alpha 2 macroglobulin is a maternally-derived immune factor in amphioxus embryos: New evidence for defense roles of maternal immune components in invertebrate chordate.Fish Shellfish Immunol. 2016, 50:21-26.

2. Xu Q, Liang Y*. Developmental Expression Patterns of Alpha 2 Macroglobulin in Amphioxus: An Insight into Liver Evolution.Ann Mar Biol Res. 2015, 2(1): 1007

3. Chao Y, Fan C,Liang YJ, Gao B, Zhang S.  A novel serpin with antithrombin-like activity       in Branchiostoma japonicum: implications for the presence of a primitive coagulation system.PLoS One. 2012, 7(3): e323921.

 4.Liang YJ*, Pan AX, Zhang SC*, Zhang Y, Liu MY. Cloning, distribution and primary immune characteristics of amphioxus alpha-2 macroglobulin.Fish Shellfish Immunol. 2011, 31(6):963-9.

5. Zhang Y, Zhang SC,Liang YJ. Identification and tissue-specific expression of a    promethin-like homolog in amphioxus Branchiostoma belcheri. Mol Biol Rep 2010, 37(5):2279-83.

6.Liang YJ, Zhang SC, Wang ZP.  Alternative complement activity in the egg cytosol of amphioxus Branchiostoma Belcheri: evidence for the defense role of maternal complement components. PLoS ONE. 2009, 4(1): e4234.

7. Ju LY, Zhang SC, Liang YJ, Sun XM. Identification, expression and antibacterial activity of a tachylectin-related homolog in amphioxus Branchiostoma belcheri with implications for involvement of the digestive system in acute phase response.Fish Shellfish Immunol. 2009, 26(2): 235-2426.

8. Zhang SC, Liang YJ, Ji G, Zhuang Z. The protochordate amphioxus is an emerging model organism for comparative immunology.Prog Nat Sci. 2009, 19(8): 923-929.

9. Guo B, Zhang SC, Wang SH,Liang YJ. Expression, mitogenic activity and regulation by growth hormone of growth hormone/insulin-like growth factor in Branchiostoma belcheri. Cell Tissue Res. 2009, 338(1):67-77.

10. Liang YJ, Zhang SC, Lun LM ,Han L. Presence and localization of antithrombin and its regulation after acute lipopolysaccharide exposure in amphioxus with implications for the origin of vertebrate liver. Cell Tissue Res. 2006, 323: 537-541.

11.Liang YJ, Zhang SC. Demonstration of plasminogen-like protein in amphioxus withimplications for the origin of vertebrate liver. Acta Zoologica (Stockhom). 2006, 87: 141-145.

12. Lun LM, Zhang SC,Liang YJ. Alanine aminotransferase in amphioxus: presence, localization and up-regulation after acute lipopolysaccharide exposure JBMB. 2006, 39 (5): 511-515.

13. Liu NG, Zhang SC, Liu ZH, Liang YJ. Identification and tissue-specific expression of amphioxus GM2  ctivator protein gene from amphioxus Branchiostoma belcheri.DNA Sequence. 2006, 17(2): 122-128.

14. Zhao BS, Zhang SC, Pang  QX,Liang YJ. Expression, purification and polyclonal antibody generation of p23, an Hsp90 cochaperone, in the amphioxus Branchiostoma belcheri.Acta oceanologica Sinica. 2006, 25: 99–105.