张宇 副教授 硕士生导师
E-mail：yuzhang@ouc.edu.cn
Tel：0532-82031387
地址：中国海洋大学鱼山校区达尔文馆319室
教育及工作经历：
2017.1-至今 中国海洋大学，海洋生命学院，副教授，硕士生导师
2014.3-2016.12 中国海洋大学，海洋生命学院，师资博士后，讲师
2009.8-2013.12 美国奥本大学，博士，水产专业
2007.9-2009.7 中国海洋大学，硕士，海洋生物学
2003.9-2007.7 中国海洋大学，学士，生物科学
研究方向：
文昌鱼进化与发育生物学
主要承担课题：
1、国家自然科学基金面上项目：“脊椎动物肝脏起源探索：文昌鱼肝盲囊的免疫-代谢互相作用与调控研究”（2020.1-2023.12），项目负责人
2、国家自然科学基金青年项目：“从文昌鱼化学防御系统分析、鉴定探索脊椎动物肝脏与化学防御系统起源”（2016.1-2018.12），项目负责人
3、山东省自然科学基金青年项目：“文昌鱼肝盲囊化学防御基因的表达调控与通路分析”（2015.7-2017.7），项目负责人
4、青岛市应用基础研究计划项目（2018.1-2019.12）：项目负责人
5、中央高校基本科研业务费青年教师科研专项基金（2015.1-2016.12）：项目负责人
6、中国博士后科学基金面上资助（2014.7-2016.6）：项目负责人
7、留学归国人员科研启动金：项目负责人
代表性论文：（#共同第一；*通讯作者）
1. Li M, Jiang C, Zhang Y*, Zhang S*. Activities of Amphioxus GH-Like Protein inOsmoregulation: Insight into Origin of Vertebrate GH Family. International Journal of Endocrinology. 2017:9538685.
2. Du X, Wang X, Wang S, Zhou Y, Zhang Y*, Zhang S*. Functional characterization of Vitellogenin_N domain, domain of unknown function 1943, and von Willebrand factor type D domain in vitellogenin of the non-bilaterian coral Euphyllia ancora: Implications for emergence of immune activity of vitellogenin in basal metazoan. Developmental and Comparative Immunology. 2017; 67:485-494
3. Wang P, Jiang C, Liu S, Cui P, Zhang Y*, Zhang S*. Trans-generationalenhancement of C-type lysozyme level in eggs of zebrafish by dietary β-glucan.Developmental and Comparative Immunology. 2017;74:25-31.
4. Liu YY, Su XR, Liu SS, Yang SS, Jiang CY, Zhang Y*, Zhang S*. Zebrafishphosvitin-derived peptide Pt5 inhibits melanogenesis via cAMP pathway. FishPhysiology and Biochemistry. 2017; 43(2):517-525.
5. Liang X, Hu Y, Feng S, Zhang S, Zhang Y*, Sun C*. Heavy chain (LvH) and lightchain (LvL) of lipovitellin (Lv) of zebrafish can both bind to bacteria andenhance phagocytosis. Developmental and Comparative Immunology. 2016; 63:47-55.
6. Lei M, Liu H, Liu S, Zhang Y*, Zhang S*. Identification and functional characterization of viperin of amphioxus Branchiostoma japonicum: Implications for ancient origin of viperin-mediated antiviral response. Developmental and Comparative Immunology. 2015; 53(2): 293-302.
7. Wang R#, Zhang Y#, Liu S, Li C, Sun L, Bao L, Feng J, Liu Z*. Analysis of 52 Rab GTPases from channel catfish and their involvement in immune responses after bacterial infections. Developmental and Comparative Immunology. 2014; 45(1):21-34.
8. Zhang Y, Liu S, Lu J, Jiang Y, Gao X, Ninwichian P, Li C, Waldbieser G, Liu Z*. Comparative genomic analysis of catfish linkage group 8 reveals two homologous chromosomes in zebrafish and other teleosts with extensive inter-chromosomal rearrangements. BMC Genomics. 2013; 14:387.
9. Zhang Y, Cong Y, Wang S, Zhang S*. Antioxidant activities of recombinant amphioxus (Branchiostoma belcheri) apolipoprotein D. Mol Biol Rep. 2011, 38(3):1847-51.
10. Bao L, Tian C, Liu S, Zhang Y, Elaswad A, Yuan Z, Khalil K, Sun F, Yang Y,Zhou T, Li N, Tan S, Zeng Q, Liu Y, Li Y, Li Y, Gao D, Dunham R, Davis K,Waldbieser G, Liu Z*. The Y chromosome sequence of the channel catfish suggestsnovel sex determination mechanisms in teleost fish. BMC Biology. 2019;17(1):6.
11. Liu Z*, Liu S, Yao J, Bao L, Zhang J, Li Y, Jiang C, Sun L, Wang R, Zhang Y,Zhou T, Zeng Q, Fu Q, Gao S, Li N, Koren S, Jiang Y, Zimin A, Xu P, Phillippy AM,Geng X, Song L, Sun F, Li C, Wang X, Chen A, Jin Y, Yuan Z, Yang Y, Tan S,Peatman E, Lu J, Qin Z, Dunham R, Li Z, Sonstegard T, Feng J, Danzmann RG,Schroeder S, Scheffler B, Duke MV, Ballard L, Kucuktas H, Kaltenboeck L, Liu H,Armbruster J, Xie Y, Kirby ML, Tian Y, Flanagan ME, Mu W, Waldbieser GC*. Thechannel catfish genome sequence provides insights into the evolution of scaleformation in teleosts. Nature Communication. 2016; 7:11757
12. Liu S, Zhang Y, Zhou Z, Waldbieser G, Sun F, Lu J, Zhang J, Jiang Y, Zhang H, Wang X, Rajendran KV, Khoo L, Kucuktas H, Peatman E, Liu Z*. Efficient assembly and annotation of the transcriptome of catfish by RNA-Seq analysis of a double haploid homozygote. BMC Genomics. 2012; 13:595.
学术专著章节：
1. Liu S, Zhang Y, Sun F, Jiang Y, Wang R, Li C, Zhang J, and Liu Z. Functional Genomics Research in Aquaculture: Principles and General Approaches. Chapter 1 in Functional Genomics in Aquaculture Published 2012 by John Wiley & Sons, Inc.
2. Zhang J, Jiang Y, Sun F, Zhang Y, Wang R, Li C, Liu S, and Liu Z. Genomic Resources for Functional Genomics in Aquaculture Species. Chapter 2 in Functional Genomics in Aquaculture Published 2012 by John Wiley & Sons, Inc.
